Clinical Trials

Lymphoma Protocols

As of July 24, 2012 - protocols do open and close daily. 
Please check with your physician for additional protocols and/or information.

1.  S0816:  A Phase II Trial of Response Adapted Therapy of Stage III-IV Hodgkin Lymphoma Using Early Interim PDG-PET Imaging

This study is investigational and is being done to find out if it is possible to use early periodic PET scans to identify those patients who are not responding to a combination of standard chemotherapy called "ABVD" (the drugs doxorubicin, bleomycin, vinblastine and dacarbazine).  This approach would allow an earlier switch to a more intensive combination chemotherapy called "BEACOPP" (the drugs bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone).  We would like to find out if the experimental treatment of switching from ABVD to BEACOPP using periodic PET scanning will improve the chances that your Hodgkin lymphoma will be cured.

2.  CALGB 50604:  A Phase II Trial of Response-Adapted Chemotherapy Based on Positron Emission Tomography for Non-Bulky Stage I and II Hodgkin Lymphoma

The purpose of this study is to find out if we can determine the type of chemotherapy that you may need for your Hodgkin lymphoma and whether or not you will need radiation therapy in addition to chemotherapy based on your response during treatment as seen on positron emission tomography (PET) scan images. A PET scan is an imaging technique that can detect the possibility of significant remaining active cancer.

For more information on these protocols or any other research, please contact your physician or our clinical research coordinator, Jessica Gerlach, CCRP at 845-333-1133